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MYP_107832
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Basic Information
PcAst-2 PcAst-1a
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
31 amino acids
C187H263N53O39
Standard
Sequence
FYPRPYRPPYLPDPRPFPRPLPAFGHEFRRH
Physicochemical Analysis
3877.42 Da
10.83
3.94
3.62
0.1269
-1.29
0.69
-0.25
95.81
28.39
0.2258
4470.00
4470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1412.47
-6.59
47.0
45.0
102.0
279.0
19.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000285 VERIFIED: YES
Provenance & Taxonomy
Louisiana crawfish [Animal]
PrAMP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Acinetobacter baumannii ATCC 19606, and Acinetobacter baumannii c.i
8 μM
MIC
PaperIdentification and Functional Characterization of the Astacidin Family of Proline-Rich Host Defence Peptides (PcAst) From the Red Swamp Crayfish (Procambarus Clarkii, Girard 1852)
RECORD: Rec_0013898 VERIFIED: YES
Provenance & Taxonomy
Louisiana crawfish [Animal]
PrAMP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
32 μM
MIC
PaperIdentification and Functional Characterization of the Astacidin Family of Proline-Rich Host Defence Peptides (PcAst) From the Red Swamp Crayfish (Procambarus Clarkii, Girard 1852)
RECORD: Rec_0024584 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 31884202 PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
RECORD: Rec_0066495 VERIFIED: YES
Provenance & Taxonomy
Louisiana crawfish [Animal]
PrAMP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 29213
32 μM
MIC
PaperIdentification and Functional Characterization of the Astacidin Family of Proline-Rich Host Defence Peptides (PcAst) From the Red Swamp Crayfish (Procambarus Clarkii, Girard 1852)
RECORD: Rec_0094428 VERIFIED: YES
Provenance & Taxonomy
Procambarus clarkii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Anti-Gram-positive Anti-Gram-negative
Escherichia coli c.i
32 μM
MIC
PMID31884202 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31884202/
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