Peptide Database

Peptide NameNukacin ISK-1

Function Ontology

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Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC116H176N32O34S4

DescriptionStandard

        GVIQTISHECRMNSWQFLFTCCS
    

Molecular Weight2691.09 Da

Isoelectric Point (pI)6.72

Net Charge (pH 7.0)-0.18

Net Charge (pH 7.4) -0.48

Charge Density (pH 7.0) -0.0078

GRAVY Index0.23

Hydrophobic Moment 0.52

Boman Index0.14

Instability Index25.39

Aliphatic Index 63.48

Aromaticity 0.1304

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1077.61

LogP -11.52

H-bond Donors 41.0

H-bond Acceptors 39.0

Rotatable Bonds 86.0

Heavy Atoms 186.0

Ring Count 5.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0312473 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus salivarius [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)