Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length366 amino acids

Chemical FormulaC1814H2841N483O519S7

DescriptionStandard

        TYPGFVVRITQAGLDYARQHGVAILEQELHQLQLPDISGDFRVRHLGKVRYELSSLKLRSFSLPSSQISPIPNVGLQVSISDAFAVVDGDWRVKVHFIRDHGSFDLKVEDLSIRISLRLGSDGSGKPTADVSECSAHVSGVSVRFSGKLSWLYNLFHSAIESVFRRTLENKVCEHVVSSAHGELQSYLRTLPVTAKIDAVAGIDYSLVAPPAAAAQSLDAELKGEFFSLARRSAVPFSPLPLAVPPDRARMVYFGASSYFFNTAGLVYHAAGALVFELTDSMIPKGLDFHLNTSTFSAFVPELEERYPDMLMKLRLSTPAAPFLSIGPEGLSLRPVVDIQAYAILPSSSLAPLFLLNLVSGTRPVM
    

Molecular Weight39944.34 Da

Isoelectric Point (pI)6.58

Net Charge (pH 7.0)-1.62

Net Charge (pH 7.4) -2.47

Charge Density (pH 7.0) -0.0044

GRAVY Index0.15

Hydrophobic Moment 0.67

Boman Index0.13

Instability Index43.43

Aliphatic Index 101.23

Aromaticity 0.0929

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 27515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177891 VERIFIED: NO

Provenance & Taxonomy

OrganismEudromia elegans [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria