Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length190 amino acids

Chemical FormulaC940H1470N252O254S9

DescriptionStandard

        PMALAMAHEPMLLLAITDFVANSAAFTYFTAGALHRNISSDMLPRRFPLQLRTKSMGVFSPQLQERYPDLPMELHLSARKQPLFSCRPDALHGALFTSAEAFVVLPNATRVPAFLLNIDAKVTGKPTISSNRLGGTPNPAYAVARSACPTPGSGGLSVPQVKKLENLLKFSLWLFGVPWANSEFCPHPVP
    

Molecular Weight20653.85 Da

Isoelectric Point (pI)9.56

Net Charge (pH 7.0)6.38

Net Charge (pH 7.4) 5.99

Charge Density (pH 7.0) 0.0336

GRAVY Index0.09

Hydrophobic Moment 0.57

Boman Index0.14

Instability Index50.89

Aliphatic Index 87.89

Aromaticity 0.0895

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7886.46

LogP -92.57

H-bond Donors 270.0

H-bond Acceptors 274.0

Rotatable Bonds 645.0

Heavy Atoms 1455.0

Ring Count 45.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117332 VERIFIED: NO

Provenance & Taxonomy

OrganismRostratula benghalensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria