Peptide Database

Peptide NameEumenine mastoparan-OD (EMP-OD; Venom peptide 1, OdVP1; Insects, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC72H120N20O18

DescriptionStandard

        GRILSFIKGLAEHL
    

Molecular Weight1553.85 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0607

GRAVY Index0.59

Hydrophobic Moment 0.60

Boman Index0.24

Instability Index5.53

Aliphatic Index 146.43

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 615.75

LogP -3.33

H-bond Donors 22.0

H-bond Acceptors 20.0

Rotatable Bonds 53.0

Heavy Atoms 110.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028758 VERIFIED: YES

Provenance & Taxonomy

OrganismOrancistrocerus drewseni [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative Hemolytic

Targetsheep erythrocytes

Activity42 %

MethodHemolysis at 50 μM

RECORD: Rec_0044644 VERIFIED: YES

Provenance & Taxonomy

OrganismOrancistrocerus drewseni [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetCandida albicans

MethodQualitative antimicrobial growth inhibition assay

RECORD: Rec_0057544 VERIFIED: YES

Provenance & Taxonomy

OrganismOrancistrocerus drewseni [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative Hemolytic

TargetCandida albicans; Botrytis cinerea; Escherichia coli; Staphylococcus aureus; sheep erythrocytes

MethodAntimicrobial growth inhibition and hemolysis assays

RECORD: Rec_0059494 VERIFIED: YES

Provenance & Taxonomy

OrganismOrancistrocerus drewseni [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

MethodQualitative antimicrobial growth inhibition assay

RECORD: Rec_0145012 VERIFIED: YES

Provenance & Taxonomy

OrganismOrancistrocerus drewseni [Animal]

Tax ID33208; 50557

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Hemolytic

TargetCandida albicans; Botrytis cinerea; Escherichia coli; Staphylococcus aureus; sheep erythrocytes

MethodAntimicrobial growth inhibition and hemolysis assays

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