Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC609H995N169O202S8

DescriptionStandard

        MTVKNKLGLIARVGATAAIATGMAVAFQPAAMAASPVVTVTPATGLSDGATVTVTGTGLTPGAVYHVAQCELVTSGTYGCDPTSVVNIAADAQGKLTTQITVHSSFAAVEGAQGTPAGTVDCKVSACQVGMGDDAGVGGGRQITFS
    

Molecular Weight14172.95 Da

Isoelectric Point (pI)5.42

Net Charge (pH 7.0)-2.36

Net Charge (pH 7.4) -2.75

Charge Density (pH 7.0) -0.0162

GRAVY Index0.43

Hydrophobic Moment 0.49

Boman Index0.26

Instability Index17.08

Aliphatic Index 83.56

Aromaticity 0.0342

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5808.43

LogP -79.12

H-bond Donors 204.0

H-bond Acceptors 210.0

Rotatable Bonds 451.0

Heavy Atoms 988.0

Ring Count 13.0

Amide Bonds 154.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203984 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces sp. ADI91-18 [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal

RECORD: Rec_0226942 VERIFIED: NO