Peptide Database

Peptide NameLipotropin beta

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC445H702N124O143S3

DescriptionStandard

        ELASELLAAAEEEEEKAQEVMAEEEEEQKQLLQEKKDGSYKMKHFRWSGPPASKRYGGFMKSWDERSQRPLLTLFKNVINKDGQQQK
    

Molecular Weight10173.27 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-3.05

Net Charge (pH 7.4) -3.31

Charge Density (pH 7.0) -0.0350

GRAVY Index-1.25

Hydrophobic Moment 0.69

Boman Index-0.27

Instability Index88.39

Aliphatic Index 55.06

Aromaticity 0.0805

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4418.00

LogP -42.99

H-bond Donors 148.0

H-bond Acceptors 144.0

Rotatable Bonds 361.0

Heavy Atoms 715.0

Ring Count 13.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076437 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

FamilyLipotropin

Tax ID8241

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0320484 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0391146 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

FamilyPOMC

Tax ID8241

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor