Peptide Database

Peptide NameNEC1_NICPL

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1124H1760N288O323S9

DescriptionStandard

        KGEVFVFPRGLVHFQKNNGKIPAAVVSAFNSQLPGTQSIPITLFGASPTVKVNGFPCKTNFTAADFSSFAISKPGATNNKFGSKVTTANVEQVPGLNTLGMAAFGIKSKIFQIMEMTILFLFAISIDRYCFAADEDMLQDVCVADLHSKVPDDVLAQTFQINIEDVQQIKSKFAPAKKFVSLARIDYAPGGINPPHTHPRASEMVFVMEGELDVGFITTANVLVSKQIT
    

Molecular Weight24764.32 Da

Isoelectric Point (pI)7.88

Net Charge (pH 7.0)1.10

Net Charge (pH 7.4) 0.60

Charge Density (pH 7.0) 0.0048

GRAVY Index0.15

Hydrophobic Moment 0.60

Boman Index0.16

Instability Index22.87

Aliphatic Index 87.29

Aromaticity 0.0961

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108903 VERIFIED: YES

Provenance & Taxonomy

OrganismNicotiana plumbaginifolia [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsGlycosylation reported

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme