Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC539H880N148O164S3

DescriptionStandard

        PDLTGHEKFGLGNIKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTISMNWNIRTWMFKDSGRATVHISKVFVTAILSTPLDNTGPTSVSLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12153.84 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index0.08

Hydrophobic Moment 0.55

Boman Index0.13

Instability Index25.87

Aliphatic Index 100.88

Aromaticity 0.0526

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4979.00

LogP -57.21

H-bond Donors 178.0

H-bond Acceptors 174.0

Rotatable Bonds 402.0

Heavy Atoms 854.0

Ring Count 16.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345670 VERIFIED: NO

Provenance & Taxonomy

OrganismAtrichornis clamosus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria