Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC125H215N39O39

DescriptionStandard

        TARLQLEARLQHLVAEILEREQSLA
    

Molecular Weight2888.28 Da

Isoelectric Point (pI)5.54

Net Charge (pH 7.0)-1.50

Net Charge (pH 7.4) -1.75

Charge Density (pH 7.0) -0.0601

GRAVY Index-0.16

Hydrophobic Moment 0.58

Boman Index-0.10

Instability Index76.37

Aliphatic Index 136.80

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1295.03

LogP -11.52

H-bond Donors 45.0

H-bond Acceptors 39.0

Rotatable Bonds 101.0

Heavy Atoms 203.0

Ring Count 1.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188144 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0415311 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman alphaherpesvirus 1 [Virus]

FamilyVirus-derived peptide

Tax ID10298;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetHerpes simplex virus 1 (Virus entry); J-nectin 1

Activity500 μM

MethodLacZ assay

PaperA heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion. | Gianni T, Menotti L, Campadelli-Fiume G. | J Virol. 2005 | PMID:15890943 PMID15890943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15890943/