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MYP_107675
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Basic Information
Defensin-like protein(Brazzein; Plants)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
54 amino acids
C276H421N77O89S8
Standard
Sequence
QDKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY
Physicochemical Analysis
6498.28 Da
6.71
-0.23
-0.63
-0.0042
-1.11
0.57
-0.31
52.18
43.33
0.1296
8940.00
9440.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2773.71
-29.09
101.0
98.0
220.0
450.0
9.0
61.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0113243 VERIFIED: YES
Provenance & Taxonomy
Pentadiplandra brazzeana [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 36082
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0117358 VERIFIED: YES
Provenance & Taxonomy
Pentadiplandra brazzeana [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Bacillus subtilis
PaperPubMed PMID 15118082 | Ming and Hellekant 1994 FEBS Lett 355: 106-108 | Kohmura et al. 1996 Biopolymers 38: 553-6 | Nat Struct Biol 1998; 5: 427-31 PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0155721 VERIFIED: YES
Provenance & Taxonomy
Pentadiplandra brazzeana [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 27217
PMID15118082 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15118082/
RECORD: Rec_0218799 VERIFIED: YES
Provenance & Taxonomy
Pentadiplandra brazzeana [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Bacillus subtilis (Gram-positive)
PMID7957951;15118082;9628478 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7957951/
RECORD: Rec_0241064 VERIFIED: YES
Provenance & Taxonomy
Pentadiplandra brazzeana [Plant]
DEFL family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
4-52; 16-37; 22-47; 26-49
Bio-Activity Profile
Antimicrobial DEFL family Antibacterial Antifungal Host defense
PaperPDB 2LY6 structural record; NMR; chain A; residues 2-54
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