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MYP_107674
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Antiviral ▸ Anti-HIV
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C90H140N26O31S3
Standard
Sequence
KTCENLADTFRGPCFATSNC
Physicochemical Analysis
2178.43 Da
6.05
-0.27
-0.52
-0.0133
-0.34
0.63
-0.07
-5.54
29.50
0.1000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.05
-13.27
35.0
34.0
68.0
150.0
3.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0206645 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Antiviral Anti-Gram-positive Anti-Gram-negative
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0206844 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0211760 VERIFIED: YES
Provenance & Taxonomy
Phaseolus lunatus [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Anticancer
PaperLunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.)
RECORD: Rec_0226945 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Phaseolus lunatus L. (lima bean)
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Colorectal Cancer (Not Available)
PMID16269344;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16269344/
RECORD: Rec_0240600 VERIFIED: YES
Provenance & Taxonomy
Phaseolus lunatus [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anticancer Cytotoxic Anti-HIV
Proteus vulgaris
81±6 μM
IC50
PaperPubMed PMID 16269344 PMID16269344 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16269344/
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