Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC544H879N151O166S4

DescriptionStandard

        PDLTGHERFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIRNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAMFSTPLDNTGPTSISLTSCQTTSGDVDIKLNGKT
    

Molecular Weight12318.97 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)3.22

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index-0.03

Hydrophobic Moment 0.58

Boman Index0.09

Instability Index19.18

Aliphatic Index 92.28

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5075.04

LogP -58.44

H-bond Donors 181.0

H-bond Acceptors 176.0

Rotatable Bonds 406.0

Heavy Atoms 865.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223797 VERIFIED: NO

Provenance & Taxonomy

OrganismPomatorhinus ruficollis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria