Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC453H719N121O128S10

DescriptionStandard

        MKIICIFLTFLITVSCGPSVSEKKRREIAERKRECYLVRGVCKTKCNTWEYIHNYCNVEPCCVLRDYQKPVMTTAAYTDKNFTDFTI
    

Molecular Weight10228.94 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)4.52

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.0519

GRAVY Index-0.18

Hydrophobic Moment 0.57

Boman Index-0.05

Instability Index39.47

Aliphatic Index 76.09

Aromaticity 0.1149

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4058.64

LogP -35.23

H-bond Donors 152.0

H-bond Acceptors 144.0

Rotatable Bonds 338.0

Heavy Atoms 712.0

Ring Count 15.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341064 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence