Peptide Database

Peptide NameAlpha-like toxin BmK-M7

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC314H484N92O90S8

DescriptionStandard

        VRDGYIALPHNCAYGCLNNEYCNNLCTKDGAKIGYCNIVGKYGNACWCIQLPDNVPIRVPGRCHPA
    

Molecular Weight7244.28 Da

Isoelectric Point (pI)8.18

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.38

Charge Density (pH 7.0) 0.0277

GRAVY Index-0.19

Hydrophobic Moment 0.45

Boman Index0.05

Instability Index42.85

Aliphatic Index 78.33

Aromaticity 0.0909

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2906.17

LogP -30.05

H-bond Donors 104.0

H-bond Acceptors 102.0

Rotatable Bonds 225.0

Heavy Atoms 504.0

Ring Count 14.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295414 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilySodium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-63; 16-36; 22-46; 26-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense

RECORD: Rec_0381229 VERIFIED: NO