MYP_107574
LL-37
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antibacterial
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Anti-Mycobacterium
Antimicrobial
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Anti-biofilm
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Biofilm inhibition
Antimicrobial
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Antifungal
Antiparasitic
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Antiprotozoal
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Anti-Trypanosoma
Antiparasitic
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General antiparasitic
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Antiparasitic
Antiviral
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Anti-Coronavirus
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Antiviral
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Anti-Filovirus
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Antiviral
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Anti-Herpesvirus
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Antiviral
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Antiviral mechanism
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Antiviral
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Antiviral mechanism
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Viral replication inhibition
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Antiviral
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Immunology
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Immune cell migration
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Chemotactic peptide
Immunology
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Immune modulation
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Immunomodulatory activity
Immunology
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Inflammation modulation
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Anti-inflammatory
Immunology
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Innate immune defense
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Host defense peptide
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Host defense activity
Membrane / Ion-channel modulation
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Sodium channel modulation
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Sodium channel inhibitor
Reproductive biology
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Contraceptive activity
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Spermicidal
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Wound healing/Regeneration
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Wound healing
Standard
37 amino acids
C205H340N60O53
Standard
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
4493.26 Da
10.61
5.76
5.55
0.1558
-0.72
0.97
-0.31
23.34
89.46
0.1081
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1901.12
-14.63
68.0
59.0
161.0
318.0
5.0
38.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0404892
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal] [Animal]; Pan troglodytes [Animal]
Cathelicidin
9606;9598
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization (N termini to C termini)
Cyclization (N termini to C termini)
Bio-Activity Profile
Entry inhibition
Inhibition of viral infection in primary macrophages
20 μM
IC50
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
RECORD: Rec_0410221
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm
Antibacterial
Staphylococcus epidermidis ATCC 35984
0.223, 1.782 μM
Crystal violet assay
RECORD: Rec_0420510
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm
Antibacterial
Pseudomonas aeruginosa
0.223 μM
Crystal violet assay
RECORD: Rec_0424368
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unformulated, A = 5 and B = 10 mg/mL particles
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Staphylococcus aureus
8-16 μg/mL
MIC
RECORD: Rec_0424847
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm
Antibacterial
Pseudomonas aeruginosa
1.782, 3.563 μM
Crystal violet assay
Showing 5 records on this page · Page 28 of 29