‹ ›
MYP_107574
← PREVIOUS NEXT → BACK
Basic Information
LL-37
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Antiviral ▸ Anti-Filovirus ▸ Anti-Ebola virus
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Antiviral ▸ Virucidal activity
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Reproductive biology ▸ Contraceptive activity ▸ Spermicidal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
37 amino acids
C205H340N60O53
Standard
Sequence
LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Physicochemical Analysis
4493.26 Da
10.61
5.76
5.55
0.1558
-0.72
0.97
-0.31
23.34
89.46
0.1081
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1901.12
-14.63
68.0
59.0
161.0
318.0
5.0
38.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0150100 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antibiofilm Antifungal
Candida albicans ATCC SC5314
32, 64 μM
XTT assay
PaperNatural and synthetic cathelicidin peptides with anti-microbial and anti-biofilm activity against Staphylococcus aureus PMID21605457
RECORD: Rec_0151633 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human RBCs
175 μg/mL
Hemolysis
PMID28408902;30076860;28400226;27367675;30076864;30043322;29022391;31417238;31396193;31016971 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28408902/
RECORD: Rec_0151813 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Natural peptide
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis strain H37Rv
5 μM
MIC
PMID23141114 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23141114/
RECORD: Rec_0154983 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
LL-37/Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
LNCaP
27
LC50
PMID24587350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24587350/
RECORD: Rec_0156250 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Escherichia coli (ATCC 25922)
25±0 μg/mL
MIC
PMID29859288 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29859288/
FIRST PREV 1 ... 9 10 11 12 13 ... 28 NEXT LAST
Showing 5 records · Page 11 of 28