Peptide Database

Peptide NameSnake venom vascular endothelial growth factor toxin VR-1

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC531H856N160O164S14

DescriptionStandard

        QVRPFLDVYERSACQTRETLVSILQEHPDEISDIFRPSCVAVLRCSGCCTDESMKCTPVGKHTADIQIMRMNPRTHSSKMEVMKFMEHTACECRPRWKQGEPEGPKEPR
    

Molecular Weight12554.36 Da

Isoelectric Point (pI)7.04

Net Charge (pH 7.0)0.06

Net Charge (pH 7.4) -0.50

Charge Density (pH 7.0) 0.0005

GRAVY Index-0.68

Hydrophobic Moment 0.68

Boman Index-0.19

Instability Index61.50

Aliphatic Index 54.50

Aromaticity 0.0459

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5211.66

LogP -56.75

H-bond Donors 188.0

H-bond Acceptors 182.0

Rotatable Bonds 416.0

Heavy Atoms 869.0

Ring Count 19.0

Amide Bonds 114.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244397 VERIFIED: YES

Provenance & Taxonomy

OrganismDaboia russelii [Animal]

FamilyPDGF/VEGF growth factor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Disulfide14-56; 45-91; 49-93

Bio-Activity Profile

Function

Cytokine Growth factor PDGF VEGF growth factor family