MYP_107490
helvecardin B
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
XXXXXXXXXXX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0250203
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
helvecardin
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
Non-proteinogenic/modified monomers: NMe-Hpg; bOH-Tyr; Hpg; Cl-Hpg; bOH-Cl-Tyr; Dhpg; Ria; D-Glc; 2OMe-Rha
Bio-Activity Profile
Antimicrobial
Anti-Gram-positive
Anti-Gram-negative
RECORD: Rec_0287583
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,2,3,4,5,6,7,8,9,10,11
Bio-Activity Profile
Antimicrobial
Antibacterial
Mycobacterium tuberculosis H37Rv
12.5-25 μM
MIC
RECORD: Rec_0330604
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,2,3,4,5,6,7,8,9,10,11
Bio-Activity Profile
Antimicrobial
Antibacterial
Murine macrophage cells RAW 264.7
46 μM
RECORD: Rec_0352523
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,2,3,4,5,6,7,8,9,10,11
Bio-Activity Profile
Antimicrobial
Antibacterial
Mycobacterium bovis BCG
14.46 μM
MIC
RECORD: Rec_0364533
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,2,3,4,5,6,7,8,9,10,11
Bio-Activity Profile
Cytotoxic
Murine macrophage cells J774A.1
62 μM
Cytotoxicity