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MYP_107486
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Basic Information
[A 1,3,13,17 ]Ple
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C133H200N36O29
Standard
Sequence
AWASFFKKAAHVAKHVAKAALTHYL
Physicochemical Analysis
2767.23 Da
10.18
4.05
3.71
0.1621
0.28
0.60
0.21
11.76
86.40
0.1600
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1028.32
-5.46
37.0
36.0
87.0
198.0
8.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073698 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Rabbit erythrocytes
100 μM
Hemolysis
PaperYoshida K, Mukai Y, Niidome T, et al. Interaction of pleurocidin and its analogs with phospholipid membrane and their antibacterial activity. J Pept Res. 2001 Feb;57(2):119-126. doi:10.1034/j.1399-3011.2001.00802.x. PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0090963 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus IFO 12732
2 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0143167 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa IFO 12582
4 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0162371 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis IFO 3143
2 μg/mL
MIC
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
RECORD: Rec_0237742 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
45 % hemolysis at 100 μM
Hemolysis
PMID11168895 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11168895/
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