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MYP_107443
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Basic Information
[F4R4]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C60H86N20O9
Standard
Sequence
FFFFRRRR
Physicochemical Analysis
1231.45 Da
12.00
3.76
3.56
0.4700
-0.85
0.10
-0.67
223.55
0.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
514.62
-2.18
21.0
13.0
39.0
89.0
4.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0068556 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360400/
RECORD: Rec_0073634 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus LAC
128 μg/mL
MIC
PMID30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360400/
RECORD: Rec_0091825 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360400/
RECORD: Rec_0139538 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Pig kidney epithelial cells LLC-PK1 (15% Killing at 100 microM
100 μM
Hemolysis
PMID30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360400/
RECORD: Rec_0189062 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
128 μg/mL
MIC
PMID30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360400/
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