Peptide Database

Peptide NameHBD3 [C11,18,23,33,40,41Y]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC252H401N75O65

DescriptionStandard

        GIINTLQKYYYRVRGGRYAVLSYLPKEEQIGKYSTRGRKYYRRKK
    

Molecular Weight5521.34 Da

Isoelectric Point (pI)10.37

Net Charge (pH 7.0)10.75

Net Charge (pH 7.4) 10.52

Charge Density (pH 7.0) 0.2389

GRAVY Index-1.21

Hydrophobic Moment 0.63

Boman Index-0.37

Instability Index43.16

Aliphatic Index 67.11

Aromaticity 0.1778

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 11920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2370.98

LogP -19.91

H-bond Donors 89.0

H-bond Acceptors 76.0

Rotatable Bonds 188.0

Heavy Atoms 392.0

Ring Count 9.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0358632 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli ATCC 25922[LC = 24.8 microg/ml

RECORD: Rec_0406404 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetBacillus cereus NCTC 2599

Activity18.7 μg/mL

MethodLC50

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