Peptide Database

Peptide NamePancreatic polypeptide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC183H282N50O55S2

DescriptionStandard

        APLEPAYPGDNATPEQMAQYAAELRKYINMVTRPRY
    

Molecular Weight4126.63 Da

Isoelectric Point (pI)6.30

Net Charge (pH 7.0)-0.20

Net Charge (pH 7.4) -0.40

Charge Density (pH 7.0) -0.0055

GRAVY Index-0.82

Hydrophobic Moment 0.77

Boman Index-0.11

Instability Index51.44

Aliphatic Index 57.22

Aromaticity 0.1111

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1692.53

LogP -15.23

H-bond Donors 56.0

H-bond Acceptors 57.0

Rotatable Bonds 126.0

Heavy Atoms 290.0

Ring Count 9.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0098838 VERIFIED: YES

Provenance & Taxonomy

OrganismSuncus murinus [Animal]

FamilyNPY

Tax ID9378

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0113143 VERIFIED: YES

Provenance & Taxonomy

OrganismSuncus murinus [Animal]

FamilyPancreatic polypeptide

Tax ID9378

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0202361 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/