Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC447H720N136O144S7

DescriptionStandard

        MRTLTILAAILLFTLQAQAESLQERADEVATQEQPGEDDQDLAVSFEENGLSTLRALGSQARRTCYCRTGRCYTPEFHSGKCVFNGRTHKLCCR
    

Molecular Weight10527.78 Da

Isoelectric Point (pI)6.08

Net Charge (pH 7.0)-1.36

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0145

GRAVY Index-0.41

Hydrophobic Moment 0.67

Boman Index-0.12

Instability Index42.38

Aliphatic Index 72.77

Aromaticity 0.0638

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4577.63

LogP -54.39

H-bond Donors 167.0

H-bond Acceptors 152.0

Rotatable Bonds 354.0

Heavy Atoms 734.0

Ring Count 10.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079621 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence