Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC430H679N117O123S13

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSAVPFTGVQELEEAGSNDTPVAAYQEMSMESKAMPGHIRPKRQSHLSLCRWCCNCCRAYKGCGFCCKF
    

Molecular Weight9872.55 Da

Isoelectric Point (pI)8.10

Net Charge (pH 7.0)1.60

Net Charge (pH 7.4) 1.13

Charge Density (pH 7.0) 0.0177

GRAVY Index0.24

Hydrophobic Moment 0.66

Boman Index0.12

Instability Index61.75

Aliphatic Index 73.78

Aromaticity 0.0889

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3808.45

LogP -37.54

H-bond Donors 141.0

H-bond Acceptors 140.0

Rotatable Bonds 322.0

Heavy Atoms 683.0

Ring Count 15.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094625 VERIFIED: NO

Provenance & Taxonomy

OrganismCyclopterus lumpus [Animal]

FamilyHepcidin

Tax ID8103

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal