Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC455H714N122O136S7

DescriptionStandard

        AVPLTLLSAILLVDLQAWTEPLQARTDEMPAQKQPPANDQDVVIYFSGDEGSSLQVRGSTKGLICHCRVLYCLFGEHLGGTCFIHGERSPICCY
    

Molecular Weight10293.73 Da

Isoelectric Point (pI)5.10

Net Charge (pH 7.0)-3.99

Net Charge (pH 7.4) -4.43

Charge Density (pH 7.0) -0.0424

GRAVY Index0.09

Hydrophobic Moment 0.43

Boman Index0.13

Instability Index55.25

Aliphatic Index 95.43

Aromaticity 0.0745

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4076.20

LogP -38.73

H-bond Donors 144.0

H-bond Acceptors 142.0

Rotatable Bonds 330.0

Heavy Atoms 720.0

Ring Count 17.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413652 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic