Peptide Database

Peptide NameCoagulation factor VIIa

Function Ontology

Hemostasis ▸ Anticoagulant activity

Hemostasis ▸ Antithrombotic activity

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1222H1921N351O383S19

DescriptionStandard

        ANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLT
    

Molecular Weight28266.68 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-7.64

Net Charge (pH 7.4) -8.58

Charge Density (pH 7.0) -0.0300

GRAVY Index-0.38

Hydrophobic Moment 0.80

Boman Index-0.03

Instability Index42.52

Aliphatic Index 77.61

Aromaticity 0.0667

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 32065.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382148 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCoagulation factor

Tax ID9606

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemostatic Coagulation factor replacement

RECORD: Rec_0403610 VERIFIED: YES