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MYP_107188
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Basic Information
Cryptonin (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C121H227N41O26S
Standard
Sequence
GLLNGLALRLGKRALKKIIKRLCR
Physicochemical Analysis
2704.42 Da
12.00
7.75
7.52
0.3228
0.14
0.94
-0.16
24.36
154.58
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1127.39
-7.73
43.0
35.0
100.0
189.0
0.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008864 VERIFIED: YES
Provenance & Taxonomy
Cryptotympana dubia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID18000874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18000874/
RECORD: Rec_0048275 VERIFIED: YES
Provenance & Taxonomy
Cryptotympana dubia [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Micrococcus luteus KCTC 3063
1.56 μg/mL
MIC
PMID18000874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18000874/
RECORD: Rec_0049660 VERIFIED: YES
Provenance & Taxonomy
Cryptotympana dubia [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida tropicalis KCTC 1925
3.12 μg/mL
MIC
PMID18000874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18000874/
RECORD: Rec_0068260 VERIFIED: YES
Provenance & Taxonomy
Cryptotympana dubia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
VRE
25 μg/mL
MIC
PMID18000874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18000874/
RECORD: Rec_0071476 VERIFIED: NO
Provenance & Taxonomy
Cryptotympana dubia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Anti-MRSA Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic Non-ribosomal
Bacillus subtilis, Candida albicans, Candida tropicalis, Escherichia coli, Micrococcus luteus, Staphylococcus aureus
Qualitative functional evidence
PMID18000874 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18000874/; https://www.uniprot.org/uniprotkb/P85028/entry; https://bblserver.org.in/ampdb/
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