Peptide Database

Peptide NameHNH nuclease

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length648 amino acids

Chemical FormulaC3117H5018N916O930S11

DescriptionStandard

        MSRNGITLPPTVVRPDKKDEYLHYLGTGNGSGPNIDFAPLVEILDMEIAFKAVSESIAQVIEVELAQVRAEGDSRVLPALESLMREMQFRDALITRKFIALLSARDIAVTRFGHAQVEIFFNGGRLPQINRRDANVSARQAYSSLFNAKLLVDGIALLNTQSVTVRGMIAVVQAQEAERIAQEQARLAAEHARQLAQEQVRAAQDQARRMAEELARIAAANEVKRLAEEQARLAAQAREQKLAEERAALEAEAEAHRLAEEKRRLQEVEQANRSLEDQRPSLSHGMPLRLQGNVANAQLVFATSRGAVAIADNLMAGSAAAIRSAVGRLAGLTAGTASGLMVGVSAFIYSPTLGNGELPERFLLSHPLSDLLSGPLPDLHRLASERALVDLPVRLSPRPLAGNLAELLVVPVGGKRLPSGVRVIAAGYNPGDNTYGTTLTDRPPTTVVWTPIIAPTDSSTQSPAEESAPPRYFGGNLVPIEGRIDTYPVPGNIHFDDFILVFPPESGLPPQYVMFRDRRNDPGVANGYGEPVVGRWLEAAAQGEGAAIPSEIAEKLRGRQFKSFRAFRERLWKAVFHEERLAELFNAASLSEMKKGKAPIVRESDFVGARVKYELHHKLGLAEGGDLYNADNISIVTPKAHIEIHKGL
    

Molecular Weight70557.48 Da

Isoelectric Point (pI)6.41

Net Charge (pH 7.0)-3.22

Net Charge (pH 7.4) -4.25

Charge Density (pH 7.0) -0.0050

GRAVY Index-0.20

Hydrophobic Moment 0.86

Boman Index-0.00

Instability Index45.89

Aliphatic Index 94.95

Aromaticity 0.0571

Extinction Coeff. Reduced 34380.00

Extinction Coeff. Oxidized 34380.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127642 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas sp. HMWF021 [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal