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MYP_107175
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Basic Information
Cathelicidin 4F, buCATHL4F
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C91H129N21O16
Standard
Sequence
AIPWSIWWRLLFKG
Physicochemical Analysis
1773.13 Da
11.00
1.79
1.61
0.1282
0.52
0.51
0.39
-11.63
118.57
0.2857
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
588.35
1.84
22.0
18.0
51.0
128.0
8.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0226051 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus NCDC-0111
6 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0282316 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MTCC 0723
200 μM
MIC
PMID26675301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26675301/
RECORD: Rec_0305962 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes ATCC-19111
3 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0306543 VERIFIED: YES
Provenance & Taxonomy
Bubalus bubalis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa NCDC-0105
50 μM
MIC
PaperDiversity, Antimicrobial Action and Structure-Activity Relationship of Buffalo Cathelicidins.
RECORD: Rec_0328075 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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