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MYP_107147
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Basic Information
[Lys]1-VmCT1-NH2 (Derived from VmCT1)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C69H109N17O16
Standard
Sequence
KLGALWNVAKSVF
Physicochemical Analysis
1432.71 Da
10.00
1.76
1.55
0.1352
0.69
0.45
0.31
23.88
120.00
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
543.67
-2.62
19.0
18.0
46.0
102.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0262722 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
100 μM
Hemolysis
PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0282465 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 12228
PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0371892 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli SBS 363
PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0380089 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae -12
PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
RECORD: Rec_0388308 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans MDM8
3.1 μM
MIC
PaperThe effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1 PMID31181304 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31181304/
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