Peptide Database

Peptide NameScolopin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC135H231N43O31S2

DescriptionStandard

        GILKKFMLHRGTKVYKMRTLSKRSH
    

Molecular Weight3016.68 Da

Isoelectric Point (pI)11.76

Net Charge (pH 7.0)7.93

Net Charge (pH 7.4) 7.62

Charge Density (pH 7.0) 0.3171

GRAVY Index-0.71

Hydrophobic Moment 0.49

Boman Index-0.28

Instability Index37.95

Aliphatic Index 74.00

Aromaticity 0.0800

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1236.03

LogP -10.05

H-bond Donors 47.0

H-bond Acceptors 43.0

Rotatable Bonds 108.0

Heavy Atoms 211.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351058 VERIFIED: YES

Provenance & Taxonomy

OrganismScolopendra subspinipes mutilans [Animal]

FamilyScolopin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis

Activity24 μM

MethodMIC

RECORD: Rec_0353612 VERIFIED: YES

Provenance & Taxonomy

OrganismScolopendra mutilans [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCandida albicans

Activity7.5 μg/mL

MethodMIC

RECORD: Rec_0356178 VERIFIED: YES

Provenance & Taxonomy

OrganismScolopendra subspinipes mutilans [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

Targetnornal and resistant B. dysenteriae ATCC 2932

Activity2.5-5.0

MethodMIC

RECORD: Rec_0373350 VERIFIED: YES

Provenance & Taxonomy

OrganismScolopendra mutilans [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetStaphylococcus aureus drug-resistant strain

Activity1 μg/mL

MethodMIC

RECORD: Rec_0377800 VERIFIED: YES

Provenance & Taxonomy

OrganismScolopendra mutilans [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

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