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MYP_107090
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Basic Information
Scolopin 2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C135H231N43O31S2
Standard
Sequence
GILKKFMLHRGTKVYKMRTLSKRSH
Physicochemical Analysis
3016.68 Da
11.76
7.93
7.62
0.3171
-0.71
0.49
-0.28
37.95
74.00
0.0800
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1236.03
-10.05
47.0
43.0
108.0
211.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0223726 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
50 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/19716842/ PMID19716842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19716842/
RECORD: Rec_0242077 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
normal and resistant Staphylococcus aureus ATCC 2576
0.5-1.0 μg/mL
MIC
PaperTwo novel antimicrobial peptides from centipede venoms.
RECORD: Rec_0246897 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-positive
Staphylococcus aureus standard strain
0.5 μg/mL
MIC
RECORD: Rec_0253423 VERIFIED: YES
Provenance & Taxonomy
Scolopendra mutilans [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli standard and drug-resistant strains
5 μg/mL
MIC
PMID19716842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19716842/
RECORD: Rec_0262003 VERIFIED: YES
Provenance & Taxonomy
Scolopendra mutilans [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Gram-negative and Gram-positive bacteria
PMID19716842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19716842/
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