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MYP_107090
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Basic Information
Scolopin 2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C135H231N43O31S2
Standard
Sequence
GILKKFMLHRGTKVYKMRTLSKRSH
Physicochemical Analysis
3016.68 Da
11.76
7.93
7.62
0.3171
-0.71
0.49
-0.28
37.95
74.00
0.0800
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1236.03
-10.05
47.0
43.0
108.0
211.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0180405 VERIFIED: YES
Provenance & Taxonomy
Scolopendra mutilans [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus dysenteriae standard strain
2.5 μg/mL
MIC
PMID19716842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19716842/
RECORD: Rec_0194156 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans ATCC 3007
7.5 μg/mL
MIC
PaperTwo novel antimicrobial peptides from centipede venoms.
RECORD: Rec_0200836 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Scolopin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli(K2Ds1)
10 μM
MIC
Paper少棘蜈蚣抗菌肽Scolopin 2-NH2的抗菌作用机制研究; Mechanism of Antimicrobial Peptide Scolopin 2-NH2 Isolated from Scolopendra subspinipes mutilans. [J].生物技术通报,2018,34(11):179-190. DOI:10.13560/j.cnki.biotech.bull.1985.2018-0476. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37201
RECORD: Rec_0211115 VERIFIED: YES
Provenance & Taxonomy
Scolopendra mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 2576
0.5 μg/mL
MIC
PMID19716842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19716842/
RECORD: Rec_0223512 VERIFIED: NO
Provenance & Taxonomy
Scolopendra subspinipes [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
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