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MYP_107088
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Basic Information
pep-gHwt30
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
30 amino acids
C149H250N46O46
Standard
Sequence
DPTARLQLEARLQHLVAEILEREQSLALHA
Physicochemical Analysis
3421.86 Da
5.42
-2.05
-2.36
-0.0684
-0.22
0.58
-0.06
65.31
130.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1497.72
-13.09
51.0
46.0
116.0
241.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045018 VERIFIED: YES
Provenance & Taxonomy
Human alphaherpesvirus 1 [Virus]
Virus-derived peptide
10298;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Fusion inhibitor
Herpes simplex virus 1 (Virus entry); J-nectin 1
50 %
LacZ assay
PaperA heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion. | Gianni T, Menotti L, Campadelli-Fiume G. | J Virol. 2005 | PMID:15890943 PMID15890943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15890943/
RECORD: Rec_0184079 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 50.0%, E 0.0%, T 30.0%, C 20.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/