Peptide Database

Peptide NameEA2x2

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC68H121N33O28S3

DescriptionStandard

        ARRCSGSGSGCGSGSGSCGRR
    

Molecular Weight1945.09 Da

Isoelectric Point (pI)10.44

Net Charge (pH 7.0)3.77

Net Charge (pH 7.4) 3.53

Charge Density (pH 7.0) 0.1793

GRAVY Index-0.78

Hydrophobic Moment 0.39

Boman Index-0.30

Instability Index79.60

Aliphatic Index 4.76

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1014.30

LogP -22.67

H-bond Donors 43.0

H-bond Acceptors 35.0

Rotatable Bonds 66.0

Heavy Atoms 132.0

Ring Count 0.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0292571 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyEA2x2

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery