Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC313H492N78O89S2

DescriptionStandard

        PDLTGYEKFGLGNVKYNISGIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWML
    

Molecular Weight6835.85 Da

Isoelectric Point (pI)7.16

Net Charge (pH 7.0)0.05

Net Charge (pH 7.4) -0.07

Charge Density (pH 7.0) 0.0008

GRAVY Index0.32

Hydrophobic Moment 0.31

Boman Index0.28

Instability Index15.42

Aliphatic Index 109.84

Aromaticity 0.0952

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2643.58

LogP -22.48

H-bond Donors 92.0

H-bond Acceptors 92.0

Rotatable Bonds 221.0

Heavy Atoms 482.0

Ring Count 12.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0109731 VERIFIED: NO

Provenance & Taxonomy

OrganismEurystomus gularis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria