‹ ›
MYP_106928
← PREVIOUS NEXT → BACK
Basic Information
Styelin-D
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
32 amino acids
C185H277N49O39
Standard
Sequence
GWLRKAAKSVGKFYYKHKYYIKAAWQIGKHAL
Physicochemical Analysis
3811.48 Da
10.24
7.92
7.60
0.2476
-0.57
0.79
-0.02
38.11
73.44
0.2188
16960.00
16960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1442.64
-5.90
53.0
49.0
126.0
273.0
11.0
32.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0020785 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Styelin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
W2 6-bromotryptophan; R4 dihydroxyarginine; K5/K8/K12/K17 dihydroxylysine; K19/K23 hydroxylysine; Y15/Y16/Y20/Y21 3,4-dihydroxyphenylalanine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PaperStyelin D, an extensively modified antimicrobial peptide from ascidian hemocytes PMID10978343 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10978343/
RECORD: Rec_0031692 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Styelin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
W2 6-bromotryptophan; R4 dihydroxyarginine; K5/K8/K12/K17 dihydroxylysine; K19/K23 hydroxylysine; Y15/Y16/Y20/Y21 3,4-dihydroxyphenylalanine
Bio-Activity Profile
Antimicrobial Toxicity
erythrocytes (species unresolved in source text)
40 μg/mL
HC50
PaperStyelin D, an extensively modified antimicrobial peptide from ascidian hemocytes PMID10978343
RECORD: Rec_0160077 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Styelin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
W2 6-bromotryptophan; R4 dihydroxyarginine; K5/K8/K12/K17 dihydroxylysine; K19/K23 hydroxylysine; Y15/Y16/Y20/Y21 3,4-dihydroxyphenylalanine
Bio-Activity Profile
Antimicrobial Toxicity
human erythrocytes
<10 μg/mL
HC50
PaperStyelin D, an extensively modified antimicrobial peptide from ascidian hemocytes PMID10978343
RECORD: Rec_0293618 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
W*=6-bromotryptophan,R**=dihydroxyarginine, Y* = 3,4-dihydroxyphenylalanine,K* = 5-hydroxylysine, K**= dihydroxylysine
Bio-Activity Profile
Antimicrobial Toxic Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0296857 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Styelin
33208; 33208
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
W2 6-bromotryptophan; R4 dihydroxyarginine; K5/K8/K12/K17 dihydroxylysine; K19/K23 hydroxylysine; Y15/Y16/Y20/Y21 3,4-dihydroxyphenylalanine
Bio-Activity Profile
Antimicrobial
PaperStyelin D, an extensively modified antimicrobial peptide from ascidian hemocytes PMID10978343
1 2 NEXT LAST
Showing 5 records · Page 1 of 2