Peptide Database

Peptide NameBeta-defensin 8

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC311H496N84O76S6

DescriptionStandard

        MRIHYLLFTFLLVLLSPLAAFSQKINDPVTYIRNGGICQYRCIGLRHKIGTCGSPFKCCK
    

Molecular Weight6820.17 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)6.62

Net Charge (pH 7.4) 6.22

Charge Density (pH 7.0) 0.1103

GRAVY Index0.37

Hydrophobic Moment 0.55

Boman Index0.15

Instability Index41.35

Aliphatic Index 104.00

Aromaticity 0.1167

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2554.62

LogP -18.73

H-bond Donors 95.0

H-bond Acceptors 91.0

Rotatable Bonds 222.0

Heavy Atoms 477.0

Ring Count 12.0

Amide Bonds 63.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0275374 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal

RECORD: Rec_0311042 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial