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MYP_106890
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Basic Information
Brevinin-2LTa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C133H229N37O38S4
Standard
Sequence
GAFGDLLKGVAKEAGMKLLNMAQCKLSGKC
Physicochemical Analysis
3082.73 Da
9.24
2.74
2.50
0.0913
0.19
0.62
0.11
-5.71
88.00
0.0333
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1218.33
-11.69
43.0
45.0
111.0
212.0
1.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093672 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Brevinin
156873
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
24-30
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
32.5 μM
MIC
PaperMolecular cloning and characterization of antimicrobial peptides from skin of the broad-folded frog, Hylarana latouchii.
RECORD: Rec_0102016 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus carnosus KHS
2 μM
MIC
PMID22426384 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22426384/
RECORD: Rec_0106452 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Psychrobacter faecalis X29
0.5 μM
MIC
PMID22426384 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22426384/
RECORD: Rec_0148057 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 1
PMID22426384 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22426384/
RECORD: Rec_0249337 VERIFIED: YES
Provenance & Taxonomy
Hylarana latouchii [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
24-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC25922
32.5 μM
MIC
PMID22426384 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22426384/
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