Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC93H167N23O23

DescriptionStandard

        LIGPVLGLVGSALGGLLKKIG
    

Molecular Weight1975.46 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0837

GRAVY Index1.40

Hydrophobic Moment 0.49

Boman Index0.56

Instability Index12.44

Aliphatic Index 180.95

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 708.80

LogP -3.66

H-bond Donors 24.0

H-bond Acceptors 25.0

Rotatable Bonds 67.0

Heavy Atoms 139.0

Ring Count 1.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0004441 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 33.3%, E 0.0%, T 47.6%, C 19.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antibacterial Antimicrobial

RECORD: Rec_0061505 VERIFIED: NO

Provenance & Taxonomy

OrganismBombina variegata [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Cytolytic Hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0093197 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina variegata [Animal]

FamilyBombinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetHas hemolytic activity against human erythrocytes

MethodHemolysis

RECORD: Rec_0241951 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina variegata [Animal]

FamilyBombinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus

RECORD: Rec_0406476 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina variegata [Animal]

FamilyBombinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli