MYP_106796
Basic Information
Cyclo(His-Tyr)
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Cardiovascular Blood pressure regulation Antihypertensive
Enzyme modulation Enzyme inhibition ACE inhibition ACE inhibitory
Enzyme modulation Enzyme inhibition DPP-IV inhibition DPP-IV inhibitory
Immunology Inflammation modulation Anti-inflammatory
Membrane / Ion-channel modulation Calcium channel modulation Calcium channel inhibitor
Metabolic Glucose metabolism Antidiabetic
Neurological / Signaling Neuropeptide activity Neuropeptide
Other / Curated residual function label Generic enzyme inhibition annotation
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Standard
2 amino acids
C15H18N4O4
Standard
Sequence
HY
Physicochemical Analysis
318.33 Da
6.74
-0.15
-0.41
-0.0769
-2.25
0.26
-0.07
224.70
0.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
141.33
-0.20
5.0
5.0
7.0
23.0
2.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0383402 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]; Amaranthus hypochondriacus [Plant]
ACE inhibitory peptide
4530, 28502
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Neuropeptide ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
RECORD: Rec_0389647 VERIFIED: NO
Provenance & Taxonomy
Oryza sativa [Plant]; Vigna radiata [Plant]
ACE-inhibitory peptide
4530;3916
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
32 mmHg
SBP decrease
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