Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC423H669N117O123S13

DescriptionStandard

        MKAFSIAVAVTLVLAFVCIVQSSAVPFTGVGELEEAGGNDTPVEAHQEVSMESWMMPKHVREKRQSHLSLCRYCCNCCKNKGCGFCCKF
    

Molecular Weight9778.39 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.69

Net Charge (pH 7.4) 0.16

Charge Density (pH 7.0) 0.0077

GRAVY Index0.16

Hydrophobic Moment 0.57

Boman Index0.10

Instability Index43.17

Aliphatic Index 71.12

Aromaticity 0.0787

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3820.87

LogP -38.84

H-bond Donors 140.0

H-bond Acceptors 140.0

Rotatable Bonds 323.0

Heavy Atoms 676.0

Ring Count 14.0

Amide Bonds 94.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0346706 VERIFIED: NO

Provenance & Taxonomy

OrganismPoecilia reticulata [Bacterium]

FamilyHepcidin

Tax ID8081

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal