Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC345H571N101O92S7

DescriptionStandard

        MKLLSLTLAALLLLSQLTPGSTQKCWNLHGRCRQKCSRKERIYVYCTNNKLCCVKPKYQPREKLWSS
    

Molecular Weight7830.30 Da

Isoelectric Point (pI)9.87

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1571

GRAVY Index-0.42

Hydrophobic Moment 0.48

Boman Index-0.15

Instability Index27.89

Aliphatic Index 87.31

Aromaticity 0.0746

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3174.69

LogP -30.04

H-bond Donors 119.0

H-bond Acceptors 111.0

Rotatable Bonds 265.0

Heavy Atoms 545.0

Ring Count 11.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395564 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence