Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length316 amino acids

Chemical FormulaC1598H2470N394O472S12

DescriptionStandard

        MNGKTGFLYNFFIKYLKKPIHRSLVTNSCPNIRAGIQLIDGDLRSPNAVMQIDDLAEVDYSLSGLPAVFQTFIDLDLKGVVFPAGNHTDSPYMAAPFTIPDQSDSMLYLAFSEYFFQSSSFAYYTAGAFNVTIAEETCSYFNINTEIFSSIIPEVAKYSITPYPVMLKLMSTEIPTISLQQDSFTVEIQGSVEVLAILPDSTAQSLFTMNIAANTSISLNIFDQKLMGSLCLNRIQFSLAHSNVGSFEVVLLENILSYIFQTEVIPSANAKLSKGFPLPNLANVTLTRPHITIVQGYVLISTDAHYKHYRRRETTC
    

Molecular Weight35137.84 Da

Isoelectric Point (pI)5.21

Net Charge (pH 7.0)-7.99

Net Charge (pH 7.4) -8.64

Charge Density (pH 7.0) -0.0253

GRAVY Index0.17

Hydrophobic Moment 0.77

Boman Index0.18

Instability Index52.38

Aliphatic Index 97.22

Aromaticity 0.1139

Extinction Coeff. Reduced 22350.00

Extinction Coeff. Oxidized 22600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216303 VERIFIED: NO

Provenance & Taxonomy

OrganismZonotrichia albicollis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence