Peptide Database

Peptide NameCyclotide protein Mra14 (Fragment)

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length179 amino acids

Chemical FormulaC825H1362N214O257S13

DescriptionStandard

        LAIFERDVITPETIEAVLKKTNPNSNIMLQEDAINALTGKTLISKTILEEAFLKNGVVGGSIPCGESCVFIPCISSVVGCSCKNKVCYKNSLALPTLEKDVITPEALEAVLKSNGGAIVNIKTIVSNTIFEEALPNNANHGLGGTIPCGESCVFIPCLTSAIGCSCKSKVCYKNSLALN
    

Molecular Weight18807.76 Da

Isoelectric Point (pI)5.90

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.72

Charge Density (pH 7.0) -0.0070

GRAVY Index0.32

Hydrophobic Moment 0.46

Boman Index0.18

Instability Index30.69

Aliphatic Index 106.20

Aromaticity 0.0391

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7491.78

LogP -89.28

H-bond Donors 262.0

H-bond Acceptors 270.0

Rotatable Bonds 628.0

Heavy Atoms 1309.0

Ring Count 17.0

Amide Bonds 194.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039850 VERIFIED: NO

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

ConfigBackbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0416714 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Tax ID344147

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial