Peptide Database

Peptide NameIA6c

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC62H115N35O18S3

DescriptionStandard

        ACRGRGRGCRGRGRGCG
    

Molecular Weight1735.00 Da

Isoelectric Point (pI)11.70

Net Charge (pH 7.0)5.77

Net Charge (pH 7.4) 5.53

Charge Density (pH 7.0) 0.3392

GRAVY Index-1.21

Hydrophobic Moment 0.49

Boman Index-0.61

Instability Index5.29

Aliphatic Index 5.88

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 900.32

LogP -16.04

H-bond Donors 39.0

H-bond Acceptors 27.0

Rotatable Bonds 60.0

Heavy Atoms 118.0

Ring Count 0.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0251471 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyIA6c

Tax ID32630

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermExtended with Alanine and an 6-aminohexanoic acid (Ahx) spacer

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery