Peptide Database

Peptide NameDefensin-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC456H729N139O134S7

DescriptionStandard

        MRTLALLAAILLLALQAQAERLPGRADQAEPEVQAEEEEQVTVISFPGEESSALQDAGVWRSEICRCRFFCGRGERRRGFCRVGLFFYSRCCR
    

Molecular Weight10526.97 Da

Isoelectric Point (pI)6.28

Net Charge (pH 7.0)-0.53

Net Charge (pH 7.4) -0.85

Charge Density (pH 7.0) -0.0057

GRAVY Index-0.15

Hydrophobic Moment 0.60

Boman Index-0.08

Instability Index68.32

Aliphatic Index 81.94

Aromaticity 0.0860

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4439.92

LogP -44.30

H-bond Donors 164.0

H-bond Acceptors 141.0

Rotatable Bonds 352.0

Heavy Atoms 736.0

Ring Count 12.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163959 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Tax ID10181

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal