Peptide Database

Peptide NameDermaseptin-PP

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC366H603N95O114S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRENENEEKQEDDEQSEEKRALWKDMLKGIGKLAGKAALGAVKTLVGAE
    

Molecular Weight8254.47 Da

Isoelectric Point (pI)5.05

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0470

GRAVY Index-0.31

Hydrophobic Moment 0.71

Boman Index-0.04

Instability Index48.85

Aliphatic Index 98.92

Aromaticity 0.0541

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3420.42

LogP -27.88

H-bond Donors 117.0

H-bond Acceptors 114.0

Rotatable Bonds 299.0

Heavy Atoms 578.0

Ring Count 5.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0309489 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa palliata [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal