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MYP_106627
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Basic Information
P2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C88H152N30O18
Standard
Sequence
KAGLAFPVGRVHRLLRK
Physicochemical Analysis
1918.34 Da
12.00
4.85
4.59
0.2850
-0.04
0.81
-0.13
38.41
114.71
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
786.55
-5.33
29.0
24.0
64.0
136.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0054318 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923[40-50% Inhibition = 133 microM]
PMID22884922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22884922/
RECORD: Rec_0058166 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Paracoccidioides brasiliensis Pb01
PMID22884922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22884922/
RECORD: Rec_0071923 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
133 μM
MIC
PMID22884922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22884922/
RECORD: Rec_0160070 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (- at NA
Hemolysis
PMID22884922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22884922/
RECORD: Rec_0164685 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Paracoccidioides brasiliensis Pb18
PMID22884922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22884922/
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